Faculty of Health and Medical Sciences

Our Research

 
    Contact us Our Research Collaborative Networks

The Centre for Cell Therapy and Regenerative Medicine (CCTRM) is a multidisciplinary research centre, with a focus on translating discoveries toward clinical benefit and better health for patients. An overview of the areas of research that CCTRM-affiliated researchers are working on can be found below. CCTRM brings together an impressive team working on chronic diseases and cancer in the lung, liver, eye, ear, skin, central nervous system and immune system. Research is focused on regeneration, therapeutic stem cell applications and delivery. Bench to bedside translation is facilitated by the industry links of key researcher, as well as the clinical positions held by the affiliated team members.

 

Astrocytes (GFAP, Red) and potential neuronal cells (Beta III Tubulin, Green) interacting within the injury site of the rat spinal cord at 1 month after moderate contusion injury. Image provided by A/Prof. Stuart Hodgetts


Lung Research


Areas of Research

  • Lung regeneration
  • Mesothelioma
  • Pulmonary fibrosis
  • Serosal repair
  • Stem cell therapies
Key Researchers


Liver Research


Areas of Research

  • Chronic liver diseases
  • Fibrosis
  • Hepatocellular carcinoma
  • Liver progenitor cells
Key Researchers


Eye Research


Areas of Research

  • Cell death mechanisms
  • Gene based therapies
  • Inherited retinal diseases
  • Retinal and macular degeneration
  • Stem cells
  • Translational research and clinical trials
Key Researchers


Ear Research


Areas of Research

  • Hearing and balance disorders
  • Regenerative cell biology
  • Stem cells transplantation
  • Scaffolds
  • Tissue engineering
Key Researchers


Orthopaedic and Musculoskeletal Research

 Areas of Research

  • Cell transplantation
  • Gene therapy
  • Muscular diseases
  • Osteoporosis
  • Osteoimmunology
  • Sarcopenia
  • Skeletal muscle repair
  • Translational research and clinical trials

Key Researchers 


Skin and Burns Research

 Areas of Research

  • Autologous skin cell therapies
  • Burn injury
  • Epithelial stem cell biology
  • Innervation and burn repair
  • Therapies for scarring and fibrosis

Key Researchers


Neuroscience Research


Areas of Research

  • Gene therapy
  • Immunomodulation
  • Neural development and repair
  • Spinal cord injury
  • Stem cell therapies
  • Tissue engineering
Key Researchers


Cancer Research


Areas of Research

  • Cancer biology and genetics
  • Hepatocellular carcinoma
  • Breast cancer
  • Ovarian cancer
Key Researchers


Scaffolds and Stem Cell Biology Research

Areas of Research

  • Extracellular matrix
  • Mechanobiology
  • Bone marrow stem cells
  • Epithelial stem cells
  • Induced pluripotent stem cells
  • Glycosaminoglycans
  • Manufacture of therapeutic goods
Key Researchers


Immunology Research

Areas of Research

  • Immune tolerance
  • Autoimmunity
Key Researchers

  • Prof. Gerard Hoyne

Keratinocytes seeded onto ECM and grown in defined serum-free medium. Pink; Collagen I, Red; Paxillin, Green; F-actin, Blue; Nuclei. Image courtesy of Chee Wai Wong.

Image provided by Rod Dilley.

Confocal image of mouse retinal section after subretinal injection with AAV.CMV.GFP. Green; AAV.CMV.GFP, Red; Muller glial cells, Blue; Nuclei. Image courtesy of Livia S Carvalho.


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